Niacinamide 500 mg®

Single Vitamin & Mineral

Brand: 21st Century

Tablet or PillSingle Vitamin and MineralOn Market

Functions

Energy & Metabolism

Product label for Niacinamide 500 mg — Click to view full label

Net Contents

110 Tablet(s)

Serving Size

1 Tablet(s)

Servings Per Container

110

Supplement Form

Tablet or Pill

Bar Code (UPC/SKU)

7 40985 22550 9

Product Version

500372-0322

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

2Active Ingredients

2 distinct active ingredients are disclosed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

2% Daily Value Coverage

2 ingredients report a %DV; 1 meet or exceed 100% DV.

4Dietary Attributes

Label states: Vegan, Vegetarian, Non-GMO, Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Tablet(s) · 1 per day

Ingredient	Amount Per Serving	% Daily Value
Niacinamide	500 mg	3125%
Calcium(Calcium Carbonate)	160 mg	12%

Not Present

Other Ingredients

CelluloseHydroxypropyl MethylcelluloseStearic AcidGum AcaciaMagnesium SilicateMagnesium StearatePolyethylene GlycolPolysorbatePolyvinyl AlcoholSilicon Dioxide

Target Groups

VeganVegetarianAdult (18 - 50 Years)Gluten FreeDairy Free

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: As a vitamin supplement, adults take one (1) tablet daily with any meal or as directed by a healthcare provider.

Warnings & Precautions

Precautions re: All Other

Do not exceed recommended dosage. Individual results may vary. Stop use and contact a physician if adverse reactions occur. Do not use if product appears to be tampered with or seal is broken.

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Precautions re: Children

Keep out of reach of children.

Storage

Store at room temperature.

Formulation

Formulation re: Other

Prolonged release Energy & circulatory support Prolonged release vitamins slowly release nutrients into the body over an extended period of time.

Formulation re: Does NOT Contain

Gluten free Non-GMO

Formula re: Contains

Niacin (Vitamin B-3) plays a role in energy metabolism. Niacinamide is a good source of Vitamin B-3 with a lower flushing effect than that of niacin.

Formulation re: Does NOT Contain

No added sugar, salt, yeast, preservatives, artificial flavors or colors.

Formulation re: Vegetarian/Vegan

Suitable for vegans.

Formulation re: Other

Guaranteed quality Laboratory tested Trusted Quality For Over 30 Years

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Vitamin Supplement

Manufacturer & Distributor

Manufacturer

21st Century HealthCare, Inc.

2119 S. Wilson St., Tempe, AZ, 85282, USA

Market Reference

$5.27 – $75.99· 40 listings

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21st Century Niacinamide 500 mg Tablets Prolonged Release - 110 ct Pack of 2
GoSupps.com4.7(2000)
$34.99
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$12.95
21st Century HealthCare - 74098522550 - Dietary Supplement Nature's Way Vitamin B3 500 mg Strength Capsule 110 per Bottle 21st Century Nutritional Pro
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$27.95
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$14.86
21st Century Flush Free Niacin 500mg 110 Capsules Pack of 2
GoSupps.com4.8(19)
$74.99

Where to Buy Locally

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Holland & Barrett - Preston
4.7 (43)
Vitamin & Supplements Shop
49 Fishergate, Preston PR1 8BH
Directions 0330 058 2640
Holland & Barrett - Lytham St Annes
3.9 (25)
Vitamin & Supplements Shop
51 St Anne's Rd W, Lytham Saint Annes FY8 1SB
Directions 0330 058 2640
Holland & Barrett - Blackburn
4.4 (20)
Vitamin & Supplements Shop
Cobden Court, 3-5 Church St, Blackburn BB1 7JG
Directions 0330 058 2640
Holland & Barrett - Accrington
4.4 (17)
Vitamin & Supplements Shop
Unit 12, Arndale Shopping Centre, Union St, Accrington BB5 1EX
Directions 0330 058 2640
Holland & Barrett - Burnley
4.5 (21)
Vitamin & Supplements Shop
33 The Mall, Burnley BB11 1BA
Directions 0330 058 2640

Research & Studies

Nicotinamide: A multifaceted molecule in skin health and beyond
L Camillo, E Zavattaro, P Savoia - Medicina, 2025 - mdpi.com
… Nicotinamide (NAM)—also known as niacinamide—is the … oral dosage of NAM is 250–500 mg/die, with a good tolerability … have proved that oral supplementation with 500 mg of NAM …
202537 citations
Pharmacologic use of niacin
J Prousky, CG Millman… - Journal of Evidence …, 2011 - journals.sagepub.com
… migraine, 300 to 500 mg of crystalline niacin can be chewed … Alternatively, 375 mg of sustained-release niacin can be taken … Physiological niacin supplements will improve skin health …
201143 citations
Nutrition for Health
WT Penberthy - leanmachine.com.au
… a previous orthomolecular publication, 500 mg of niacin 3x daily (… inexpensively by supplemental niacin or niacinamide. … at the beginning of the 21st century either as a therapeutic …
Niacin
M Meyer-Ficca, JB Kirkland - Advances in Nutrition, 2016 - academic.oup.com
… These results indicate that a therapeutic increase of NAD concentrations might prevent age-associated health decline and that dietary supplementation with niacin as the major …
2016112 citations
Exploring niacinamide as a multifunctional agent for skin health and rejuvenation
K Kapoor, S Shankar, RF Begum… - Current …, 2025 - benthamdirect.com
… the inflammatory response, niacinamide supplementation helps to reduce inflammation [9]. … Orally, nicotinamide has demonstrated efficacy at 500 mg twice daily for reducing actinic …
20255 citations
5 Niacin
JB Kirkland - Handbook of vitamins, 2013 - books.google.com
… skin flushing, which, alone, does not reflect serious health risks. Many B vitamin … supplement users are found to exceed the UL for niacin [38]. Nicotinic acid supplements of up to 500 mg …
201370 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2025-03-25. DSLD Label ID: 326336. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.