Evening Primrose Oil®

Botanicals & Herbs

Brand: 21st Century

Softgel CapsuleBotanicalOn Market
Click to view full label

Net Contents

60 Softgel(s)

Serving Size

1 Softgel(s)

Servings Per Container

60

Supplement Form

Softgel Capsule

Bar Code (UPC/SKU)

7 40985 21828 0

Product Version

500055-0916N

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1Dietary Attributes

Label states: Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Softgel(s) · 3 per day

IngredientAmount Per Serving
Evening Primrose Seed Oil Concentrate(Oenothera biennis Seed Oil)500 mg

Not Present

Other Ingredients

GelatinGlycerinWater, Purified

Target Groups

Adult Female (18 - 50 Years)Gluten Free

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: As a herbal supplement, adults take one (1) softgel with any meal, three (3) times daily or as directed by a healthcare provider. Do not exceed recommended dosage. Individual results may vary.

Warnings & Precautions

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Precautions re: All Other

Stop use and contact a physician if adverse reactions occur.

Precautions re: Children

Keep out of reach of children.

Precautions re: All Other

Do not use if product appears to be tampered with or seal is broken.

Precautions re: Allergies

May contain soy ingredients.

Storage

Storage

Store in a cool, dry place.

Formulation

Formulation re: Does NOT Contain

No added sugar, salt, yeast, preservatives or artificial flavors.

Formula re: Type

Women's health support

Formulation re: Does NOT Contain

Gluten free

Formula re: Contains

Evening Primrose Oil is a source of gamma-linolenic acid (GLA), an essential fatty acid that has been used to support women's health.

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. this product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Herbal Supplement

Other Label Statements

Seals/Symbols

Guaranteed Quality Laboratory Tested

Manufacturer & Distributor

Manufacturer

21st Century HealthCare, Inc.

2119 S. Wilson St., Tempe, AZ, 85282, USA

Market Reference

$6.88 – $161.70· 40 listings
  • 21st Century Evening Primrose Oil Softgels

    21st-century-vitamins4.7(2000)
    $8.49
  • Spring Valley Women's Standardized Evening Primrose Oil Health Dietary Supplement

    Walmart4.5(30)
    $6.88Lowest
  • Evening Primrose Oil mg Now

    Vitacost.com4.8(3100)
    $8.56
  • Sports Research Evening Primrose Oil

    Sports Research4.8(1000)
    $21.95
  • Evening Primrose Oil

    Valley Women's Health
    $34.99
  • Evening Primrose Oil Softgels

    Thrive Wellness Center3.7(3)
    $66.00
  • E.P.O. Evening Primrose Oil Softgels

    Milltown Pharmacy4.8(42)
    $33.00
  • Nature's Truth Cold Pressed Evening Primrose Oil

    Walmart4.8(147)
    $9.99

Where to Buy Locally

Enter your city or ZIP code to find supplement & health stores in your area that may carry this product.

Showing representative supplement & health retailers — search above for stores in your area.

  • The Vitamin Shoppe

    4.5 (75)

    Vitamin & supplements store

    10 University Blvd W, Silver Spring, MD 20901

  • Nutrition Club MD (Lilly Mendez) Herbalife

    4.8 (57)

    Vitamin & supplements store

    1425 University Blvd E, Hyattsville, MD 20783

  • GNC

    2.9 (30)

    Vitamin & supplements store

    13733 Connecticut Ave, Wheaton-Glenmont, MD 20906

  • The Vitamin Shoppe

    4.6 (157)

    Vitamin & supplements store

    1803 Rockville Pike, Rockville, MD 20852

  • GNC

    3.3 (13)

    Vitamin & supplements store

    8661 Colesville Rd Suite D181, Silver Spring, MD 20910

  • The Vitamin Shoppe

    4.4 (161)

    Vitamin & supplements store

    9101 Alaking Ct Suite 100, Capitol Heights, MD 20743

  • GNC

    4.6 (164)

    Vitamin & supplements store

    3500 East-West Hwy, Hyattsville, MD 20782

  • The Vitamin Shoppe

    4.4 (105)

    Vitamin & supplements store

    2460 Market St NE #701, Washington, DC 20018

Research & Studies

  • The effect of Oenothera biennis (Evening primrose) oil on inflammatory diseases: a systematic review of clinical trials

    M Sharifi, N Nourani, S Sanaie… - … Medicine and Therapies, 2024 - Springer

    Background Evening primrose oil (EPO), extracted from the seeds of Oenothera biennis, has gained attention for its therapeutic effects in various inflammatory conditions. Method We …

    202430 citations
  • Evening Primrose (Oenothera biennis) Biological Activity Dependent on Chemical Composition

    M Timoszuk, K Bielawska, E Skrzydlewska - Antioxidants, 2018 - mdpi.com

    … Generally, evening primrose oil is obtained from Oenothera … The biological effect of evening primrose oil is a result of its … Evening primrose oil contains over 70% linoleic acid (LA) and …

    2018212 citations
  • Biological activities of evening primrose oil

    HE Tahir, GK Mahunu, AA Mariod, Z Xiaobo… - … seed oils, 2022 - Elsevier

    … In the last decades, many unconventional oils have attracted great attention due to higher biological compounds. Evening primrose oil (Oenothera biennis) is commonly utilized as …

    20225 citations
  • The Effect of Evening Primrose Oil on Menopausal Symptoms Management: A Systematic Review and Meta-Analysis

    M Larki, S Mohammadi, S Makvandi - Journal of Caring Sciences, 2025 - jcs.tbzmed.ac.ir

    … to the health risks, deciding to pursue herbal alternatives. This meta-analysis aimed to determine the effectiveness of evening primrose oil (EPO) in managing menopausal symptoms. …

    20251 citations
  • Evening primrose oil

    B Bayles, R Usatine - 2009 - digitalcommons.tamusa.edu

    … the oil also is used for several women’s health conditions, including breast pain (mastalgia), menopausal and premenstrual symptoms, cervical ripening, and labor induction or …

    2009168 citations
  • Studies on the cultivation and uses of evening primrose (Oenothera spp.) in China

    YC Deng, HM Hua, J Li, P Lapinskas - Economic Botany, 2001 - Springer

    … We believe that evening primrose oil and GLA have an important role to play in human nutrition, health care, and cosmetics, and especially in relation to a variety of common diseases, …

    200181 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2024-10-24. DSLD Label ID: 304099. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.