E 450 mg (1000 IU)®

Vitamins

Brand: 21st Century

Softgel CapsuleVitaminOn Market
Click to view full label

Net Contents

55 Softgel(s)

Serving Size

1 Softgel(s)

Servings Per Container

Not specified

Supplement Form

Softgel Capsule

Bar Code (UPC/SKU)

7 40985 22324 6

Product Version

500050-0418N

Label Analysis

Objective insights generated automatically from the official DSLD label — a quick, factual read of how this product is formulated and disclosed.

1Active Ingredients

Single-ingredient formula listed in Supplement Facts.

100%Amount Transparency

Every active ingredient discloses a specific amount per serving.

1% Daily Value Coverage

1 ingredients report a %DV; 1 meet or exceed 100% DV.

1Dietary Attributes

Label states: Gluten-Free.

This analysis is generated algorithmically from label data for educational reference only. It is not a product endorsement, ranking, or medical advice.

Allergen Guide

Contains

  • Soy

Free From

  • Gluten

Allergen flags are parsed automatically from the official label's claims and statements. Always verify against the physical product label before use, especially if you have a severe allergy.

Supplement Facts

Serving Size: 1 Softgel(s) · 1 per day

IngredientAmount Per Serving% Daily Value
Vitamin E(DL-Alpha-Tocopheryl Acetate)450 mg3000%

Not Present

Other Ingredients

GelatinGlycerinrefined Soybean Oilpurified Water

Target Groups

Adult (18 - 50 Years)Gluten Free

Label Claims

NutrientAll OtherStructure/Function

Directions & Suggested Use

Suggested/Recommended/Usage/Directions

Directions: As a vitamin supplement, adults take one (1) softgel daily with any meal or as directed by a healthcare provider. Do not exceed recommended dosage.

Warnings & Precautions

Precautions re: All Other

Do not exceed recommended dosage.

Precautions re: Pregnant or Nursing or Prescription Medications

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Precautions re: All Other

Stop use and contact a physician if adverse reactions occur.

Precautions re: Children

Keep out of reach of children.

Precautions re: All Other

Do not use if product appears to be tampered with or seal is broken.

Precautions re: Allergies

Contains soy.

Storage

Storage

Store at room temperature.

Formulation

Formulation re: Does NOT Contain

No added Sugar, Salt, Yeast, Preservatives, Artificial Flavors or Colors.

Formulation re: Does NOT Contain

Gluten free

Formula re: Contains

Contains soy.

Formula re: Contains

Vitamin E is an antioxidant nutrient and supports the immune system.

FDA Statements

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Vitamin Supplement

Other Label Statements

General Statements: All Other Content

Individual results may vary.

General Statements: All Other Content

Antioxidant Support

Seals/Symbols

Gluten free

Seals/Symbols

Guaranteed quality Laboratory tested

Manufacturer & Distributor

Manufacturer

21st Century HealthCare, Inc.

2119 S. Wilson St., Tempe, AZ, 85282, USA

Market Reference

$5.99 – $39.99· 16 listings
  • 21st Century Softgels

    iHerb4.7(287)
    $10.99
  • 21st Century E 450 mg (1000 IU) 55 Softgels

    GoSupps.com4.7(287)
    $29.99
  • 21st Century Natural Softgels

    21st-century-vitamins4.7(5400)
    $15.99
  • 21st Century E-400 Softgels

    Swanson Health Products4.7(4900)
    $17.99
  • 21st Century 400Iu Softgels

    Walmart - Pharma Frills
    $21.42
  • 21st Century One Daily Essential Tablets

    iHerb4.7(938)
    $5.99Lowest
  • 21st Century Vitamin E 180mg Softgels 110ct

    AmericanPharmaWholesale.com5.0(11)
    $6.32
  • Mazen Online One Daily Men's Health Tablets

    Nicolas Care
    $22.00

Where to Buy Locally

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Research & Studies

  • Vitamin E: A cure in search of recognition

    AW Saul - Journal of orthomolecular medicine, 2003 - isom.ca

    … thrombosis with 450 to 1,600 IU; angina with 450 to 1,600 IU; … “All statements of nutritional support for dietary supplements … hundred IUs of vitamin E would be good public health policy. …

    200313 citations
  • Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality

    …, RA Riemersma, LJ Appel, E Guallar - Annals of internal …, 2005 - acpjournals.org

    … in the 2 vitamin E groups to the average dosage of 600 IU/d. … of any form of supplementary α-tocopherol per day (… the generalizability of our findings to healthy adult populations. Finally, …

    20053,794 citations
  • Vitamin E in human health and disease

    MW Clarke, JR Burnett, KD Croft - Critical reviews in clinical …, 2008 - Taylor & Francis

    … E are expressed in international units per milligram (IU/mg). The … The efficacy of vitamin E supplements in preventing platelet … mg of RRR-α-TOH and 500 mg of a mixed TOH supplement …

    2008293 citations
  • Dietary supplements and disease prevention—a global overview

    S Rautiainen, JAE Manson, AH Lichtenstein… - Nature Reviews …, 2016 - nature.com

    … Health Initiative (WHI) reported low calcium intake (<800 mg … vitamin D (400 IU per day) and calcium (1,000 mg per day) … found that administration of 1,000 IU of vitamin D daily had no …

    2016377 citations
  • Dietary Supplements in Pregnancy and Postpartum: Evidence, Safety Challenges and a Precision Nutrition Framework (GAPSS)

    J Chen, M Duan, Z Zhu, R Su, J Cai - Antioxidants, 2026 - mdpi.com

    … trials of high-dose vitamins C + E (1000 mg + 400 IU) have consistently shown no reduction in … In conclusion, optimal maternal and foetal health in the 21st century will not be achieved …

    20262 citations
  • … safety of multivitamin and mineral supplement use to prevent cancer and chronic disease in adults: a systematic review for a National Institutes of Health state-of-the …

    HY Huang, B Caballero, S Chang… - Annals of internal …, 2006 - acpjournals.org

    … C, vitamin E, β-carotene, selenium, and zinc reduced the rate of cancer by 31% in men but not in women. Multivitamin and mineral supplements … and mineral supplements were evident. …

    2006343 citations

Data sourced from the U.S. National Institutes of Health, Office of Dietary Supplements Dietary Supplement Label Database (DSLD) · Label entered 2019-08-23. DSLD Label ID: 205875. This information is provided for educational reference only and is not medical advice. Always follow the product label and consult a doctor or pharmacist before use.